Product name | Vardenafil hydrochloride |
Other Name | 1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-piperazine dihydrochloride;VARDENAFIL;VARDENAFIL, HYDROCHLORIDE SALT;vardenafil hydrochloride;VARDENAFIL HCL;Vardenafil Hydrochloride Trihydrate 224785-90-4 /;Levitra,Valdenafil.HCl;1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-piperazine; Levitra; Staxyn; Vivanza |
Original | China |
CAS | 224785-91-5 |
Molecular formula | C23H33ClN6O4S |
Leading time | within 5 work days upon receipt of payment |
Delivery | Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS |
Purity | 99% |
Package | Discreet and Hidden package according to specific requirement |
Appearance | White Powder |
Certification | SGS, ISO 9001, KOSHER |
Payment Terms | , Money Gram , T/T, Bitcoin |
Minimum Order Quantity | 5g |
Price | Negotiable |
Usage | It is used for treating erectile dysfunction and premature ejaculation. |
Molecular structure |
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Description
Vardenafil (INN) is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to Sildenafil citrate (Viagra) and Tadalafil (Cialis). The difference between the Vardenafil molecule and Sildenafil citrate is that a nitrogen atom has different position and the change of Sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both Sildenafil and Vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than Sildenafil's.
Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with Vardenafil might provoke potentially life-threatening hypotension (low blood pressure).
Further, Vardenafil lengthens QT interval. Therefore it should not be taken by men taking other medications that affect the QT interval (such as Amiodarone).
Application
Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's.
Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from penetration to ejaculation.
It is available in 2.5 mg, 5 mg, 10 mg, and 20 mg doses in round orange tablets. The normal starting dose is 10 mg (roughly equivalent to 50 mg of sildenafil). Vardenafil should be taken 1 to 2 hours prior to sexual activity, with a maximum dose frequency of once per day. In some territories, such as the UK, only certain doses may be available.
Vardenafil is also available under the name Staxyn as a tablet which dissolves on the tongue rather than being swallowed in the form of a pill.
The recommended dosage of Staxyn is one 10 mg tablet taken 60 minutes before sexual activity. Certain antidepressants, antifungal, antibiotic, heart, and blood pressure medications can interact with Staxyn. Tell your doctor all medications you use.
Specification
est Items | Specification | Test Results |
Description | White or almost white crystalline powder | White crystalline powder |
Melting Point | 191.0~193.0℃ | 192℃ |
Loss of drying | ≤1.0% | 0.5% |
Heavy Metal | ≤20ppm | 15ppm |
TLC | Only one spot | Only one spot |
Assay | ≥99.5% | 99.91% |
Conclusion | It complies with the USP 35. |