|Apprarance||White crystalline powder|
|usage||RAD140 is an investigational selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting.|
RAD140 demonstrates excellent affinity for the androgen receptor (Ki = 7 nM) as well as good selectivity over other steroid hormone nuclear receptors , with the closest off target receptor being the progesterone receptor (IC50 = 750 nM) . RAD140 is a novel SARM with high affinity and specificity for AR , is orally available, and exhibits potent anabolic effects in rodents and nonhuman primates.
The stability of RAD140 is high (t1/2 > 2 h) in incubations with rat , monkey , and human microsomes , and it also had good bioavailability in rats and monkeys. RAD140 is also neuroprotective using the rat kainate lesion model . RAD140 is shown to exhibit peripheral tissue-specific androgen action that largely spared prostate , neural efficacy by activation of androgenic gene regulation effects , and neuroprotection of hippocampal neurons against cell death caused by systemic administration of the excitotoxin kainate.
According to the Cambridge-based pharmaceuticals company Radius , the potent , orally bioavailable and nonsteroidal RAD 140 SARM is designed to make the hormonal receptors in the tissues of the body act the same way as if they're getting a good dose of testosterone , setting off the same effects as if you're cycling with prohormones and anabolic steroids minus unwanted side effects.
Moreover , clinical studies also show that RAD 140 SARM also has a few other benefits , which we will discuss more thoroughly in a moment.
Enhanced speed , stamina and endurance during high-intensity workoutsFaster buildup of muscular tissues that helps you achieve more gains in a shorter period of timeBased on medical tests , RAD 140 SARM also displayed a greater anabolic effect than testosterone when used . Researchers pointed out that besides having a more "reinforced" effect than testosterone , RAD 140 SARM was also seen to help reduce the androgenic side effects that can be potentially caused by the same on the prostate.