| Product Name | Finasteride |
| Synonyms | PROSCAR;PROSTIDE;N-(2-METHYL-2-PROPYL)-3-OXO-4-AZA-5ALPHA-ANDROST-1-ENE-17BETA-CARBOXAMIDE;MK-906;(5alpha,17beta)-(1,1-dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide;17beta-(n-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one;4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5-alpha,17-be;4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5alpha,17beta |
| CAS NO | 98319-26-7 |
| MF | C23H36N2O2 |
| MW | 372.54 |
| Purity | >99% |
| Storage temp | -20°C Freezer |
| Chemical Properties | Off-White Crystalline Powder |
| Product Categories | Pharmaceutical Intermediates |
| Lead time | Within 3 work days upon receipt of payment |
| Shipment | EMS, DHL, TNT, FedEx, UPS |
| Uses | Treatment of benign prostatic hyperplasia and androgenetic alopecia |
| Product Categories | Active Pharmaceutical Ingredients;API;Biochemistry;Steroids;Steroids (Others);Intermediates & Fine Chemicals;Pharmaceuticals;Vitamin Ingredients;Intracellular receptor;Steroid and Hormone;PROSCAR;Hormone Drugs |
Description
Finasteride is China a benign prostatic hyperplasia and prostatitis based drug treatment, it is 4 - nitrogen steroid hormone compounds of the synthesis, belonging to resistance hormone drugs, can be selective inhibition of 5α- reductase, enable the conversion of testosterone into resistance 5α dihydrotestosterone (DHT), front row in glandular cells of the male hormone levels drop, reduce the serum prostate specific antigen, reduce the prostate volume increased, urine flow increased, thereby reducing symptoms to achieve the purpose for the treatment of benign prostatic hyperplasia.Prostatic hyperplasia is called hypertrophy of the prostate, leading to the bladder neck and urethra oppressed, causing urinary tract obstruction and other symptoms and complications, so that patients feel pain, multiple men over the age of 50.
Application
Finasteride is a 5α- reductase inhibitor, is hormone resistant drugs, it can prevent converts testosterone todihydrotestosterone (DHT), so as to reduce of DHT synthesis, reduce the content of scalp hair and serum dihydrotestosterone. Germinal function recovery has been suppressed follicular papilla, promoting hair growth and preventing hair loss, finasteride is currently approved by the U.S. Food and Drug Administration (FDA) only for male pattern hair loss of oral drug treatment, the recommended dose is 1mg.
Specification
COA:
| Test Items | Specification |
Test Results |
|
Description |
White or off-white crystalline powder |
Off-white crystalline powder |
|
Specific rotation |
-56°~-60° |
-58.2° |
|
Identification |
IR |
Matches with working standard |
Complies |
HPLC |
|||
Solubility |
Freely soluble in chloroform and in alcohol; Very slightly soluble in water |
Conform |
|
Heavy metals |
≤10ppm |
<10ppm |
|
Water |
≤0.3% |
0.22% |
|
Residue on ignition |
≤0.1% |
0.05% |
|
Relative material |
Maximum impurities≤0.5% |
0.36% |
|
Total impurities≤1.0% |
0.52% |
||
Assay |
98.5~101.0% |
99.68% |
|
Conclusion |
The specification conform with Enterprise standard |
||
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