Product Name:L-Thyroxine
Alias : Levothyroxine; L-Epinephrine HCl; epinephrine hydrochloride; L-adrenaline hydrochloride; (R)-adrenaline hydrochloride
CAS NO. : 51-48-9
EINECS : 200-101-1
MF : C15H11I4NO4
MW : 776.87
Melting Point : 223ºC(DEC.)
Purity : 98%
Appearance : White crystalline powder
Grade : Pharmaceutical Grade & Veterinary Grade
Storage: Shading, Closed preservation
Delivery time : Within 24 hours upon receipt of payment
Shipment : EMS, DHL, TNT, FedEx, UPS
Usage : Levothyroxine is typically used to treat hypothyroidism. Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.
Description
Levothyroxine (INN, USAN) or L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated cholesterol levels) but was withdrawn due to cardiac side effects.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Levothyroxine (INN, USAN) or L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated cholesterol levels) but was withdrawn due to cardiac side effects.
Levothyroxine is typically used to treat hypothyroidism, and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy. It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing. Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion. In 1992, President George H.W. Bush told television host Larry King that he had been prescribed levothyroxine as part of a treatment regimen for Graves' disease.
Side effects: This medication should not be used for weight loss. Normal doses of this medication will not work for weight loss, and large doses of this medication may cause serious, possibly fatal side effects, especially when taken with diet pills.
Application
Levothyroxine is typically used to treat hypothyroidism,and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy.It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing.Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion
Specification
COA:
Product name | L-Thyroxine | |
Appearance | White crystalline powder | |
Assay(*) | 98~101.0% | 99.3% |
Identification | By UV, To match with working standard | Complies |
Related Substances | Not more than the reference solution (0.05%) | Complies |
Heavy metals | ≤10ppm | 10ppm |
Loss on drying | <0.5% | 0.15% |
Resiue on ignition | ≤0.1% | 0.05% |
Melting | 235°C | Complies |