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Anti-parasitic Active Pharmaceutical Intermediates Raw Chlorhexidine Gluconate CAS 18472-51-0

Anti-parasitic Active Pharmaceutical Intermediates Raw Chlorhexidine Gluconate CAS 18472-51-0

Anti-parasitic Active Pharmaceutical Intermediates Raw Chlorhexidine Gluconate CAS 18472-51-0

Product Details:

Place of Origin: China
Brand Name: Rund
Certification: ISO9001 , KOSHER , SGS
Model Number: CAS 18472-51-0

Payment & Shipping Terms:

Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: 10g/50g/100g/500g/1000g/foil bag, 25kg/drum
Delivery Time: Within 24h after confirming the payment
Payment Terms: T/T, Western Union, MoneyGram, BTCOIN
Supply Ability: 1000kg per month
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Detailed Product Description
Product Name: Chlorhexidine Gluconate CAS: 18472-51-0
MF: C34H54Cl2N10O14 MW: 897.7572
Appearance: Pale-yellow Liquid Storage: Store In Cool Place

Anti-parasitic Active Pharmaceutical Intermediates Raw Chlorhexidine Gluconate CAS 18472-51-0 

Details:
 
Product Name Chlorhexidine Gluconate
Alias Chlorhexidine digluconate; N'',N'''''-hexane-1,6-diylbis(1-{(1E)-amino[(4-chlorophenyl)amino]methylidene}guanidine) - D-gluconic acid (1:2); N'',N'''''-hexane-1,6-diylbis(1-{(1E)-amino[(4-chlorophenyl)amino]methylidene}guanidine) - D-gluconic acid (1:1); N,N''''-hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)]-hexonic acid (1:2)
MF C34H54Cl2N10O14
MW 897.7572
CAS 18472-51-0
Molecular Structure Raw Chlorhexidine Gluconate Pharmaceutical Intermediates CAS 18472-51-0
Appearance Almost transparent colorless or pale yellow slightly sticky liquid. Odourless or almost odourless
 
Description:
 

HUMAN HEALTH: Surgical scrubs, surgical wipes, surgical lubricants, dental preparations for treatment of gingivitis, hand soaps, skin preparations and cosmetics.

 

Animal Health & Nutrition: Pet Shampoos, teat dips, lubricants, horse scrubs and solutions to treat skin conditions in both companion animals and livestock.

 

Applications
 

Chlorhexidine digluconate is commercially available as a 20% (w/v) aqueous solution since the substance cannot be isolated as a solid. It is soluble in water to at least 50% (w/v) but high viscosity makes such concentrated solutions inconvenient to use. Autoclaving of solutions greater than 1.0% can result in the formation of insoluble residues and is therefore unsuitable.

 

If sterile solutions are required at such high concentrations, then filtration through a 0.22 m membrane filter is recommended. Dilute chlorhexidine solutions may be stored at room temperature, and a shelf-life of at least 1 year can be expected, provided that the packaging is adequate. Prolonged exposure to high temperature or light is to be avoided because this can adversely affect the stability of chlorhexidine solutions. All dilute solutions to be stored should be either heat-treated (sterilized or pasteurized) or chemically preserved (4% isopropanol or 7% ethanol) to eliminate the possibility of microbial contamination. For autoclaved solutions the choice of container material is important, best results being achieved with neutral glass or polypropylene. If soda glass is used with chlorhexidine solutions the resultant pH may be above that which is considered optimal for stability (pH 5-7)because of leaching of alkaline materials from the bottle".

 
Specification
 
Name Chlorhexidine digluconate Check number 20150705
Batch No. 150705A06 Quantity 250kg
MFG date 2015.07.05 Specification P1507026
Test date 2014.06.11 Report date 2014.06.11
Appearance This product is light yellow to clarify for almost slightly sticky stiff liquid; odorless or almost odorless. Conform Conform
Relative density Should be 1.060-1.070 1.0673 Conform
Identification Identification (1), (2), (3) should be positive reaction positive reaction Conform
Checking
acidity 5% (ml/ml) aqueous solution pH value should be 5.5-7.0 6.9 Conform
P-chloroaniline The color of the test solution should not be deeper than the control solution (≤ 0.25%) Conform Conform
Related substances Test spots should be shallow impurities in the control (1) the main spots, compared with the control (1) the main spots deep in spots 1-2 impurities should be shallower than the control (2) the main spots Conform Conform
Residue on ignition ≤0.1% Conform Conform
Microbial Limit Bacterial≤100cfu/ml <1cfu/ml Conform
Enzyme/microzyme<10cfu/ml <1cfu/ml
Staphylococcus glucose aureus, Pseudomonas aeruginosa, white cocci were not detected Negative
Assay This product contains chlorhexidine gluconate (C12H30Cl2N10-2C6H12O7) should be 19.0-21.0% (g/ml) 19.8% C conform
Conclusion Conform with CP2010

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