|Place of Origin:||China|
|Minimum Order Quantity:||10g|
|Packaging Details:||10g 50g 100g 500g 1kg|
|Delivery Time:||3-7 days|
|Payment Terms:||T/T, , MoneyGram, BTCcoin|
|Supply Ability:||1kg --100kg|
|Grade:||Pharmaceutical Grade||Storage:||Shading, Confined Preservation|
|Assay:||98%||Appearance:||White Crystalline Powder|
active pharmaceutical ingredient,
andriol testosterone undecanoate
Product name: Anastrozole
Alias :Arimidex ,Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl)1,3-benzenediacetionitrile
CAS : 120511-73-1
Assay : 98%~102%
Appearance : White crystalline powder
Active life cycle : 6 hours
MF : C17H19N5
MW : 293.37
Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Delivery time :within 24 hours upon receipt of payment
Delivery: EMS, DHL, TNT, FedEx, UPS
Usage : Anastrozole is a potent non-steroidal aromatase inhibitors , which lead the decrease of plasma level of estrogen, inhibited the growth of breast cancer. For the treatment of advanced breast cancer in postmenopausal women patients.
Anastrozole is a drug indicated in the treatment of breast cancer in post-menopausal women. It is used both in adjuvant therapy (i.e. following surgery) and in metastatic breast cancer.
Many breast cancers also contain aromatase; the importance of tumor-generated estrogens is uncertain. Treatment of breast cancer has included efforts to decrease estrogen levels by ovariectomy premenopausally and by use of anti-estrogens and progestational agents both pre- and post-menopausally, and these interventions lead to decreased tumor mass or delayed progression of tumor growth in some women. Anastrozole is a potent and selective non-steroidal aromatase inhibitor. It significantly lowers serum estradiol concentrations and has no detectable effect on formation of adrenal corticosteroids or aldosterone.
Three azole aromatase inhibitors are potent selective, it can inhibit the cytochrome P-450 dependent aromatase thereby blocking the biosynthesis of estrogen, but estrogen is the main factor that stimulates the growth of breast cancer cells.
The treatment of breast cancer, especially for those with adjuvant hormone therapy after menopause after recurrence of women with advanced breast cancer.
Although Arimidex does increase testosterone levels slightly in the body, it is more often used in conjunction with other steroids to lower estrogen in the body. Many anabolic steroids will convert, or aromatize, in the body into estrogen, which causes many of the unwanted side effects like bloating and acne. Arimidex is one of the best compounds to lower the aromatizing effect of steroids.
As to female. Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers can be treated with drugs that block the effects of these hormones. Arimidex blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.
As to male. Anastrozole may also be a part of treatment for men suffering from prostate cancer. In rare cases when a male patient has breast cancer, anastrozole may also be a treatment option. It is also a good choice for the treatment of men hair loss.
As to bodybuilders. Another use of Anastrozole for men is to maintain a powerfully-built and bulky physique among bodybuilders, especially those who take anabolic steroids. One function of steroids is that it mimics the actions of naturally occurring testosterone, resulting in the increase of protein levels, muscle buildup, and strength improvement.
|Description||White crystalline powder||Complies|
|Solubility||Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile||Complies|
|Total Unspecified Impurity||max. 0.2%||0.08%|
|Individual unspecified impurlty||max. 0.1%||0.05%|
|Related compound B||max. 0.2%||0.07%|
|Related compound C||max. 0.2%||0.04%|
|Related compound D||max. 0.1%||0.05%|
|Related compound E||max. 0.1%||0.06%|
|Limit of cyclohexane||max. 0.08%||ND|
|Limit of ethylacetate||max. 0.1%||0.07%|
|Residue on ignition||max. 0.1%||0.07%|
|Storage||Cool and dry|
|Conclusion||It complies to USP32 .|
Contact Person: Mr. Dr. Zhang