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446292-07-5, C21H21N3O5,610-200-5,Pharmaceuticals,Intermediate of Rivaroxaban

446292-07-5, C21H21N3O5,610-200-5,Pharmaceuticals,Intermediate of Rivaroxaban

  • 446292-07-5,	C21H21N3O5,610-200-5,Pharmaceuticals,Intermediate of Rivaroxaban
446292-07-5,	C21H21N3O5,610-200-5,Pharmaceuticals,Intermediate of Rivaroxaban
Product Details:
Place of Origin: China
Brand Name: RUN
Certification: ISO9001
Model Number: RUN-Z
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: inquiry
Packaging Details: 10g 50g 100g 500g 1kg
Delivery Time: 3-7 days
Payment Terms: T/T, , MoneyGram, BTCcoin
Supply Ability: 1kg --100kg
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Detailed Product Description
Product Name: 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- Synonyms: 2-[(2R)-2-hydroxy-3-{[4-(3-oxoMorpholin-4-yl)phenyl]aMino}p Ropyl]-1H-isoindole-1,3(2H)-dione;(R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)-amino)propyl)isoindoline-1,3-dione;Rivaroxaban InterMediate B;2-[(2R)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]
CAS: 446292-07-5 MF: C21H21N3O5
MW: 395.41 EINECS: 610-200-5
Boiling Point: 734.9±60.0 °C(Predicted) Density: 1.421
Purity: 99% Form: Solid
Color: White
High Light:

methenolone enanthate powder


testosterone propionate powder

SECTION 1: Basic information

1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- Basic information
Synonyms: Rivaroxaban Impurity 10/4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone;1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]-;4-[((2R)-Hydroxy-3-phthaliMido)propylaMine]phenyl-3-Morpholinone;2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione;2-[(2R)-2-hydroxy-3-{[4-(3-oxoMorpholin-4-yl)phenyl]aMino}p ropyl]-1H-isoindole-1,3(2H)-dione;(R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)-amino)propyl)isoindoline-1,3-dione;Rivaroxaban interMediate B;2-[(2R)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl]isoindole-1,3-dione
CAS: 446292-07-5
MF: C21H21N3O5
MW: 395.41
EINECS: 610-200-5
Product Categories: Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Intermediate of Rivaroxaban
Mol File: 446292-07-5.mol
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- Chemical Properties
Boiling point 734.9±60.0 °C(Predicted)
density 1.421
pka 13.91±0.20(Predicted)

SECTION 2: Hazard identification

2.1 Classification of the substance or mixture

Not classified.

2.2 GHS label elements, including precautionary statements

Pictogram(s) No symbol.
Signal word No signal word
Hazard statement(s) none
Precautionary statement(s)
Prevention none
Response none
Storage none
Disposal none

2.3 Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
2-((2R)-2-Hydroxy-3-{[4-(3-oxo-4-morpholinyl) phenyl]amino}propyl)-1H-isoindole-1,3(2H)-dione 2-((2R)-2-Hydroxy-3-{[4-(3-oxo-4-morpholinyl) phenyl]amino}propyl)-1H-isoindole-1,3(2H)-dione 446292-07-5 610-200-5 100%

SECTION 4: First-aid measures

4.1 Description of necessary first-aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

no data available

SECTION 5: Fire-fighting measures

5.1 Suitable extinguishing media

Use dry chemical, carbon dioxide or alcohol-resistant foam.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

6.2 Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

7.2 Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).

Skin protection

Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.

Thermal hazards

no data available


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