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848133-35-7 Amines Trans-4-Dimethylaminocrotonic Acid Hydrochloride C6H12ClNO2

848133-35-7 Amines Trans-4-Dimethylaminocrotonic Acid Hydrochloride C6H12ClNO2

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    848133-35-7 Pharmaceutical Intermediates


    C6H12ClNO2 Pharmaceutical Intermediates


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  • Product Name
    Trans-4-Dimethylaminocrotonic Acid Hydrochloride
  • Synonyms
    Trans-4-Dimethylaminocrotonic;trans-4-dimethylaminocrotonic Acid Hydrochloride Salt;2-Butenoic Acid,4-(dimethylamino)-, Hydrochloride (1:1), (2E)-;trans-4-Dimethylaminocrotonic Acid Hydrochloride(848133-35-7)
  • CAS
  • MF
  • MW
  • Melting Point
    162 °C
  • Purity
  • Place of Origin
  • Brand Name
  • Certification
  • Model Number
  • Minimum Order Quantity
  • Price
  • Packaging Details
    10g 50g 100g 500g 1kg
  • Delivery Time
    3-7 days
  • Payment Terms
    T/T, MoneyGram, BTCcoin
  • Supply Ability
    1kg --100kg

848133-35-7 Amines Trans-4-Dimethylaminocrotonic Acid Hydrochloride C6H12ClNO2

SECTION 1: Basic information

trans-4-Dimethylaminocrotonic acid hydrochloride Basic information
Product Name: trans-4-Dimethylaminocrotonic acid hydrochloride
Synonyms: 2E)-4-(Dimethylamino)-2-butenoic acid hydrochloride;Afatinib int-2 Trans-4-Dimethylaminocrotonic acid hydrochloride;2-Butenoic acid, 4-(dimethylamino)-, (2E)-, hydrochloride;trans-4-Dimethylaminocrotonic acid hydrochloride, >=97%;trans-4-Dimethylaminocrotonic;trans-4-dimethylaminocrotonic acid hydrochloride salt;2-Butenoic acid,4-(dimethylamino)-, hydrochloride (1:1), (2E)-;trans-4-Dimethylaminocrotonic acid hydrochloride(848133-35-7)
CAS: 848133-35-7
MF: C6H12ClNO2
MW: 165.62
EINECS: 617-631-8
Product Categories: Others chemical reagents;Amines;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 848133-35-7.mol
trans-4-Dimethylaminocrotonic acid hydrochloride Structure
trans-4-Dimethylaminocrotonic acid hydrochloride Chemical Properties
Melting point 162 °C

SECTION 2: Hazard identification

2.1 Classification of the substance or mixture

Skin corrosion, Sub-category 1B

2.2 GHS label elements, including precautionary statements

Pictogram(s) 848133-35-7 Amines Trans-4-Dimethylaminocrotonic Acid Hydrochloride C6H12ClNO2 1
Signal word Danger
Hazard statement(s) H314 Causes severe skin burns and eye damage
Precautionary statement(s)

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P264 Wash ... thoroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...


P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P363 Wash contaminated clothing before reuse.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P316 Get emergency medical help immediately.

P321 Specific treatment (see ... on this label).

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

2.3 Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
2-Butenoic acid, 4-(dimethylamino)-, hydrochloride, (2E)- (9CI) 2-Butenoic acid, 4-(dimethylamino)-, hydrochloride, (2E)- (9CI) 848133-35-7 617-631-8 100%

SECTION 4: First-aid measures

4.1 Description of necessary first-aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

no data available

SECTION 5: Fire-fighting measures

5.1 Suitable extinguishing media

Use dry chemical, carbon dioxide or alcohol-resistant foam.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

6.2 Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

7.2 Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).

Skin protection

Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.

Thermal hazards

no data available