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Cas 302964-24-5 2-Amino-N-(2-Chloro-6-Methylphenyl)Thiazole-5-Carboxamide C11H10ClN3OS Dasatinib

Cas 302964-24-5 2-Amino-N-(2-Chloro-6-Methylphenyl)Thiazole-5-Carboxamide C11H10ClN3OS Dasatinib

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    Cas 302964-24-5 Pharmaceutical Intermediates

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    C11H10ClN3OS Pharmaceutical Intermediates

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    Dasatinib Pharmaceutical Intermediates

  • CAS
    302964-24-5
  • MF
    C11H10ClN3OS
  • MW
    267.73
  • EINECS
    1806241-263-5
  • Product Categories
    Dasatinib;API Intermediates
  • Melting Point
    208.0 To 212.0 °C
  • Boiling Point
    362.0±37.0 °C(Predicted)
  • Density
    1.474±0.06 G/cm3(Predicted)
  • Pka
    11.09±0.70(Predicted)
  • Place of Origin
    China
  • Brand Name
    RUN
  • Certification
    IOS9001
  • Model Number
    RUN-Z
  • Minimum Order Quantity
    10g
  • Price
    enquiry
  • Packaging Details
    10g 50g 100g 500g 1kg
  • Delivery Time
    3-7 days
  • Payment Terms
    T/T, MoneyGram, BTCcoin
  • Supply Ability
    1kg --100kg

Cas 302964-24-5 2-Amino-N-(2-Chloro-6-Methylphenyl)Thiazole-5-Carboxamide C11H10ClN3OS Dasatinib

  • Cas 302964-24-5 2-Amino-N-(2-Chloro-6-Methylphenyl)Thiazole-5-Carboxamide C11H10ClN3OS Dasatinib
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SECTION 1: Basic information

2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide Basic information
Product Name: 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
Synonyms: 2-Amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide 98%;Dasatinib IMpurity 2;2-AMino-N-(2-chloro-6-Methylphenyl)thiazole-5-carboxiMide);2-Amino-5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazole, 2-Amino-5-[(6-chloro-o-tolyl)carbamoyl]-1,3-thiazole;5-ThiazolecarboxaMide,2-aMino-N-(2-chloro-6-Methylphenyl);Dasatinib Int N-2;2-AMino-N-(2-chloro-6-Meth;2-AMino-N-(2-chloro-6-Methylphenyl)-5-thiazolecarboxaMide
CAS: 302964-24-5
MF: C11H10ClN3OS
MW: 267.73
EINECS: 1806241-263-5
Product Categories: Dasatinib;API intermediates
Mol File: 302964-24-5.mol
2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide Structure
 
2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide Chemical Properties
Melting point 208.0 to 212.0 °C
Boiling point 362.0±37.0 °C(Predicted)
density 1.474±0.06 g/cm3(Predicted)
pka 11.09±0.70(Predicted)
CAS DataBase Reference 302964-24-5(CAS DataBase Reference)

SECTION 2: Hazard identification

2.1Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

2.2GHS label elements, including precautionary statements

Pictogram(s) Cas 302964-24-5 2-Amino-N-(2-Chloro-6-Methylphenyl)Thiazole-5-Carboxamide C11H10ClN3OS Dasatinib 1
Signal word Warning
Hazard statement(s)

H315 Causes skin irritation

H319 Causes serious eye irritation
Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response

P302+P352 IF ON SKIN: Wash with plenty of water/...

P321 Specific treatment (see ... on this label).

P332+P317 If skin irritation occurs: Get medical help.

P362+P364 Take off contaminated clothing and wash it before reuse.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal none

2.3Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

3.1Substances

Chemical name Common names and synonyms CAS number EC number Concentration
2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 302964-24-5 608-455-2 100%

SECTION 4: First-aid measures

4.1Description of necessary first-aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

4.2Most important symptoms/effects, acute and delayed

no data available

4.3Indication of immediate medical attention and special treatment needed, if necessary

no data available

SECTION 5: Fire-fighting measures

5.1Suitable extinguishing media

Use dry chemical, carbon dioxide or alcohol-resistant foam.

5.2Specific hazards arising from the chemical

no data available

5.3Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

SECTION 6: Accidental release measures

6.1Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

6.2Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.

6.3Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

SECTION 7: Handling and storage

7.1Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

7.2Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

SECTION 8: Exposure controls/personal protection

8.1Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

8.3Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).

Skin protection

Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.

Thermal hazards

no data available

 

 

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