Shanghai fine-chemistry CO., Ltd 86-21-17617767348-1 jyzhang@api-chem.com
302964-08-5 N-(2-Chloro-6-Methylphenyl)-2-[(6-Chloro-2-Methyl-4-Pyrimidinyl)Amino]-5-Thiazolecarboxamide C16H13Cl2N5OS

302964-08-5 N-(2-Chloro-6-Methylphenyl)-2-[(6-Chloro-2-Methyl-4-Pyrimidinyl)Amino]-5-Thiazolecarboxamide C16H13Cl2N5OS

  • High Light

    302964-08-5 Pharmaceutical Intermediates

    ,

    C16H13Cl2N5OS Pharmaceutical Intermediates

    ,

    IOS9001 Pharmaceutical Intermediates

  • CAS
    302964-08-5
  • MF
    C16H13Cl2N5OS
  • MW
    394.28
  • EINECS
    695-686-7
  • Melting Point
    333-335°C
  • Density
    1.516±0.06 G/cm3(Predicted)
  • Storage Temp
    -20°C Freezer
  • Pka
    10.92±0.70(Predicted)
  • Place of Origin
    China
  • Brand Name
    RUN
  • Certification
    IOS9001
  • Model Number
    RUN-Z
  • Minimum Order Quantity
    10g
  • Price
    enquiry
  • Packaging Details
    10g 50g 100g 500g 1kg
  • Delivery Time
    3-7 days
  • Payment Terms
    T/T, MoneyGram, BTCcoin
  • Supply Ability
    1kg --100kg

302964-08-5 N-(2-Chloro-6-Methylphenyl)-2-[(6-Chloro-2-Methyl-4-Pyrimidinyl)Amino]-5-Thiazolecarboxamide C16H13Cl2N5OS

Product Name: N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide
Synonyms: Dasatinib Int N-1;N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-yrimidinyl)amino]-5-thiazolecarboxamide;N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino];dasatinib Dichloro;2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95%;CAY10697;N-(2-Chloro-6-methyl-phenyl)-2-[(6-chloro-2-methyl-pyrimidin-4-yl)amino]thiazole-5-carboxamide;N-(2-CHLORO-6-METHYLPHENYL)-2-[(6-CHLORO-2-METHYL-4-PYRIMIDINYL)AMINO]-5-THIAZOLECARBOXAMIDE
CAS: 302964-08-5
MF: C16H13Cl2N5OS
MW: 394.28
EINECS: 695-686-7
Product Categories: Dasatinib;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds

Hazard identification


Classification of the substance or mixture

Reproductive toxicity, Category 1B

Specific target organ toxicity – repeated exposure, Category 1

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1


GHS label elements, including precautionary statements

Pictogram(s) 302964-08-5 N-(2-Chloro-6-Methylphenyl)-2-[(6-Chloro-2-Methyl-4-Pyrimidinyl)Amino]-5-Thiazolecarboxamide C16H13Cl2N5OS 0 302964-08-5 N-(2-Chloro-6-Methylphenyl)-2-[(6-Chloro-2-Methyl-4-Pyrimidinyl)Amino]-5-Thiazolecarboxamide C16H13Cl2N5OS 1
Signal word Danger
Hazard statement(s)

H360 May damage fertility or the unborn child

H372 Causes damage to organs through prolonged or repeated exposure

H410 Very toxic to aquatic life with long lasting effects

Precautionary statement(s)
Prevention

P203 Obtain, read and follow all safety instructions before use.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P273 Avoid release to the environment.

Response

P318 IF exposed or concerned, get medical advice.

P319 Get medical help if you feel unwell.

P391 Collect spillage.

Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.


Other hazards which do not result in classification

no data available

Composition/information on ingredients


Substances

Chemical name Common names and synonyms CAS number EC number Concentration
2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide 302964-08-5 695-686-7 100%

First-aid measures


Description of necessary first-aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.


Most important symptoms/effects, acute and delayed

no data available


Indication of immediate medical attention and special treatment needed, if necessary

no data available

Fire-fighting measures


Suitable extinguishing media

Use dry chemical, carbon dioxide or alcohol-resistant foam.


Specific hazards arising from the chemical

no data available


Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

Accidental release measures


Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.


Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.


Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

Handling and storage


Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.


Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

Exposure controls/personal protection


Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available


Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.


Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).

Skin protection

Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.

Thermal hazards

no data available